Эта публикация цитируется в 7 статьях

Communications

Iron(iii) chloride-catalyzed mechanochemical cascade synthesis of highly-substituted pyrrolyl indoles

A. Mukherjee^a, D. S. Kopchuk^ab, S. Santra^a, A. Majee^c, G. V. Zyryanov^ab, O. N. Chupakhin<sup>ab

a</sup> Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
^b I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^c Department of Chemistry, Visva-Bharati University, Santiniketan, West Bengal, India

Аннотация: Iron(iii) chloride has been found to serve as an efficient catalyst for a mechanochemical (ball milling) one-pot four- component cascade reaction of phenyl glyoxal, anilines, indoles and activated alkyne affording highly-substituted 3-(1H-pyrrol-2-yl)-1H-indoles. The procedure is beneficial because of mild conditions, easily available starting materials, cheap catalyst and possibility for scaling.

Ключевые слова: ball milling, mechanochemical reactions, multicomponent reactions, cascade reactions, indoles, multi-substituted 3-(1H-pyrrol-2-yl)-1H-indoles, gram-scale synthesis.

Язык публикации: английский

DOI: 10.1016/j.mencom.2022.09.018

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