Эта публикация цитируется в 1 статье

Communications

Synthesis of 3-imino-1-benzazepines by the cyanide-incorporating heterocyclization of (2-benzylaminobenzylidene)malonates

D. S. Ivanov^a, M. V. Molchanova^a, A. Yu. Smirnov^ab, A. A. Mikhaylov^ab, P. N. Solyev^c, M. S. Baranov<sup>ab

a</sup> M. M. Shemyakin–Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russian Federation
^b N. I. Pirogov Russian National Research Medical University, 117997 Moscow, Russian Federation
^c V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russian Federation

Аннотация: A method for the synthesis of 1,2,3,5-tetrahydro-4H-1-benzazepine-4,4-dicarboxylates from 2-[2-(N-benzyl-N-methylamino)benzylidene]malonates and trimethylsilyl cyanide is proposed. The transformation can be considered as the 1,5-hydride shift–cyclization cascade sequence involving the formation of intermediate stable boronate complex.

Ключевые слова: 1-benzazepines, 1,5-hydride shift, cyanide ion, tert-amino effect, (benzylidene)malonates, heterocyclization.

Поступила в редакцию: 18.04.2025
Принята в печать: 29.05.2025

Язык публикации: английский

DOI: 10.71267/mencom.7805

Реферативные базы данных:

•