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ЖУРНАЛЫ // Mendeleev Communications // Архив

Mendeleev Commun., 2025, том 35, выпуск 4, страницы 437–439 (Mi mendc6414)

Эта публикация цитируется в 1 статье

Communications

Determination of critical micelle concentrations of Pluronics

N. P. Iakimov, E. O. Fomin, N. S. Melik-Nubarov, I. D. Grozdova

Department of Chemistry, M. V. Lomonosov Moscow State University, 119991 Moscow, Russian Federation


Аннотация: Critical micelle concentrations (CMCs) of Pluronics were determined by three techniques, namely 1,6-diphenyl-1,3,5-hexatriene fluorescence, sensitization of multidrug-resistant cancer cells with Pluronic unimers and a novel technique based on the migration of fluorophore-labeled lipid from liposomes into Pluronic micelles. The CMCs of each Pluronic determined by the three methods differ by no more than 30% and are consistent with data reported by different research teams. A literature review revealed a widely cited dataset of CMC values that differ significantly from data reported by other research groups, including ours.

Ключевые слова: Pluronics, critical micelle concentration, 1,6-diphenyl-1,3,5-hexatriene (DPH) fluorescence, multidrug resistance, liposome–micelle lipid migration.

Поступила в редакцию: 21.11.2024
Принята в печать: 04.02.2025

Язык публикации: английский

DOI: 10.71267/mencom.7689



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