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ЖУРНАЛЫ // Mendeleev Communications // Архив

Mendeleev Commun., 2023, том 33, выпуск 6, страницы 784–785 (Mi mendc524)

Эта публикация цитируется в 2 статьях

Communications

N + PC strategy for the synthesis of phosphinic pseudopeptides incorporating glycine isostere

S. R. Golovash, A. V. Borodachev, M. E. Dmitriev, V. V. Ragulin

Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation


Аннотация: The reaction between dialkyl methylenebiscarbamates and phosphonous carboxylic acids affords N-protected phosphinic pseudopeptides incorporating glycine isostere. The compounds obtained are promising building blocks for subsequent peptide modification.

Ключевые слова: phosphinic pseudopeptides, dialkyl methylenebiscarbamates, phosphonous carboxylic acids, glycine isostere, amidoalkylation.

Язык публикации: английский

DOI: 10.1016/j.mencom.2023.10.015



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