Эта публикация цитируется в 16 статьях

Communications

Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity

N. R. Khasiyatullina, V. F. Mironov, S. K. Gumerova, A. D. Voloshina, A. S. Sapunova

A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation

Аннотация: A new efficient method for the synthesis of 1,4-dihydroxy-2-naphthylmethyl-and 1,4-dioxo-2(1H,4H)-2-naphthylmethyl-phosphonium salts by reactions of 2-methyl-1,4-naphtho-quinone with appropriate P–H-phosphonium trifluoroacetates has been suggested. The reactions were carried out under mild conditions and provided high yields of target compounds. Representative reaction products have been found to possess moderate antimicrobial and antitumor activity.

Язык публикации: английский

DOI: 10.1016/j.mencom.2019.07.027

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