Эта публикация цитируется в 5 статьях

Communications

Trifluoroacetyl substituted pyrazolotriazines: synthesis and pathways of formation

E. V. Sadchikova^ab, D. L. Alexeeva^a, V. G. Nenajdenko<sup>c

a</sup> Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
^b Ural State Medical University, Ekaterinburg, Russian Federation
^c Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Аннотация: The reaction of 4-dimethylamino-1,1,1-trifluorobut-3-en-2one with 3-arylpyrazole-5-diazonium salt in MeCN affords 7-aryl-3-(trifluoroacetyl)pyrazolo[5,1-c][1,2,4]triazines. The transformation of relative 5-diazopyrazoles leads to 4-hydroxy-1,4-dihydropyrazolo[5,1-c][1,2,4]triazine derivatives, while the reaction in acidic aqueous solution results in 4,4,4-trifluoro-3-oxo-2-(pyrazol-5-ylhydrazono)butanals.

Ключевые слова: pyrazoles, diazo compounds, diazonium salts, enones, pyrazolo[5,1-c][1,2,4]triazines, trifluoromethyl group.

Язык публикации: английский

DOI: 10.1016/j.mencom.2020.03.016

Реферативные базы данных:

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