50th anniversary of the Institute for Nuclear Research, RAS. Instruments and methods of investigation Radioisotope research and development at the Linear Accelerator of the Institute for Nuclear Research of RAS
Abstract:
Radioisotope research at the linear accelerator of INR RAS has been developing since 1989. In 1992, a facility for the irradiation of isotope targets and radioisotope production was built, operating on an extracted proton beam with an energy of 160 MeV and a current of more than 120 $\mu$A, which was the most productive facility in the world at that time. The facility is used for both fundamental and applied research. The main focus is the study of the processes of the generation and recovery of medical radioisotopes, as well as the development of technology for their production. The main radionuclides produced now are strontium-82 and actinium-225. A Russian $^{82}{\rm Sr}/^{82}{\rm Rb}$ generator for PET-diagnostics has been developed by INR RAS and is being introduced in medicine. New types of $^{225}{\rm Ac}/^{213}{\rm Bi}$ generators are also being developed for the treatment of oncological diseases. In addition, the study of the process for the production and chemical recovery of medical radionuclides $\rm ^{117m}Sn$, $^{68}{\rm Ge}$, $^{72}{\rm Se}$, $^{64, 67}{\rm Cu}$, $^{223}{\rm Ra}$, $^{230}{\rm Pa}$, and $^{230}{\rm U}$ is being carried out, as is the study of some generators with these isotopes. The technology developed at INR is used in Russia and abroad. Physical processes of proton interaction with different nuclei are also investigated in the laboratory of the radioisotope complex of INR RAS. The produced $^{22}{\rm Na}$, $^{83}{\rm Rb}$, $^{109}{\rm Cd}$, and radioactive sources with these radionuclides are used in physical research and technology.
Keywords:radioisotopes, linear accelerator of protons, fundamental and applied research, nuclear medicine, strontium-82, rubidium-82 generator, actinium-225, bismuth-213 generator.
PACS:28.60.+s, 29.20.Ej, 87.56.bd
Received:March 12, 2021 Revised:July 6, 2021 Accepted: July 7, 2021
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