This article is cited in 38 papers

CONFERENCES AND SYMPOSIA

Methods of biomedical optical imaging: from subcellular structures to tissues and organs

I. V. Turchin

Institute of Applied Physics, Russian Academy of Sciences, Nizhny Novgorod

Abstract: Optical bioimaging methods have a wide range of applications in the life sciences, most notably including the molecular resolution study of subcellular structures, small animal molecular imaging, and structural and functional clinical diagnostics of tissue layers and organs. We review fluorescent microscopy, fluorescent macroscopy, optical coherence tomography, optoacoustic tomography, and optical diffuse spectroscopy and tomography from the standpoint of physical fundamentals, applications, and progress.

Keywords: optical bioimaging, biophotonics, optical coherence tomography, fluorescent microscopy, optical nanoscopy, optoacoustics, optical diffusion tomography, fluorescent agents, fluorescent proteins, upconversion nanoparticles, STED, STORM.

PACS: 42.25.Dd, 42.62.Be, 43.35.Sx, 87.64.-t, 87.64.Cc

Received: January 22, 2016
Accepted: December 7, 2015

DOI: 10.3367/UFNr.2015.12.037734

 English version: Physics–Uspekhi, 2016, 59:5, 487–501

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