A. V. Ivachtchenko, “Sulfonyl modulators of serotonin 5-HT<nobr>$_{6}$</nobr> receptors and their pharmacophore models”, Usp. Khim., 2014, Volume 83, Issue 5,Pages <nobr>439

This article is cited in 13 papers

Sulfonyl modulators of serotonin 5-HT$_{6}$ receptors and their pharmacophore models

A. V. Ivachtchenko^abc

^a Chemical Diversity Research Institute
^b ChemDiv, Inc.
^c Aniveuro Pharmaceuticals, Inc., San Diego, CA, USA

Abstract: The data on the syntheses of serotonin 5-HT$_{6}$ receptor modulators published in recent years are surveyed. Modulators with high affinity to 5-HT$_{6}$ receptors with different selectivity degrees ranging from highly selective to semi selective and multimodal are described. The results of clinical trials of the most promising 5-HT$_{6}$ receptor modulators that arouse most interest in medicinal chemists are also described.
Bibliography — 128 references.

Received: 27.01.2013

DOI: 10.1070/RC2014v083n05ABEH004371