This article is cited in 13 papers

The experience and prospects of melphalan and sarcolysin nano-sised drug delivery systems creation

V. P. Krasnov^a, M. A. Korolyova^a, E. L. Vodovozova<sup>b

a</sup> I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of Russian Academy of Sciences, Ekaterinburg
^b M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow

Abstract: The results of experimental studies concerned with the development of nano-sized drug delivery systems of antitumor drugs sarcolysin and melphalan are generalized. The structures and biological activities of nanocarriers in comparison with unmodified drugs are discussed. Particular attention is given to the liposomes containing lipid derivatives of sarcolysin and melphalan in the lipid bilayer.
Bibliography — 196 references.

Received: 31.10.2012

DOI: 10.1070/RC2013v082n08ABEH004358

 English version: Russian Chemical Reviews, 2013, 82:8, 783–814

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