This article is cited in 19 papers

Methods for the synthesis of oligonucleotides containing reactive electrophilic groups

A. V. Kachalova, E. M. Zubin, T. S. Oretskaya

Lomonosov Moscow State University, Faculty of Chemistry

Abstract: The published data on the methods of chemical synthesis of oligonucleotides containing 5'- and 3'-terminal or internal carboxy or aldehyde functional groups are considered. The known methods are systematised and their advantages and disadvantages are discussed. The bibliography includes 65 references.

Received: 20.06.2002

DOI: 10.1070/RC2002v071n12ABEH000742

 English version: Russian Chemical Reviews, 2002, 71:12, 1041–1059

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