This article is cited in 7 papers

Advances in the Chemistry of α,α,α',α'-Tetrasubstituted Piperidines

L. N. Yakhontov

All-Union Scientific Research Chemical-Pharmaceutical Institute, Moscow

Abstract: The stages in the development of the chemistry of piperidines with a sterically hindered nitrogen atom and the practical importance of compounds of this class are examined. The methods of synthesis of 2,2,6,6-tetra-alkylpiperidines published in the literature, and their chemical properties and reactions are surveyed: processes occurring without the growth of a carbon skeleton, condensations with the formation of new C–C bonds, and reactions involving a change in the heterocyclic skeleton of the molecules. The characteristics of the stereochemistry and in particular of the conformations of 2,2,6,6-tetrasubstituted piperidines are analysed.
The bibliography includes 174 references.

UDC: 547.834

DOI: 10.1070/RC1984v053n08ABEH003098

 English version: Russian Chemical Reviews, 1984, 53:8, 757–767

Bibliographic databases:

• 
•