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JOURNALS // Uspekhi Khimii // Archive

Usp. Khim., 1969 Volume 38, Issue 11, Pages 1989–2015 (Mi rcr2310)

This article is cited in 18 papers

The Chemistry of O-alkyl Derivatives of Lactams

R. G. Glushkov, V. G. Granik

All-Union Scientific Research Chemical-Pharmaceutical Institute, Moscow

Abstract: The review gives a general account of the methods of synthesis and chemical properties of O-alkyl derivatives of lactams: lactim ethers, lactam acetals, and others. The reactions of O-alkyl derivatives of lactams with various nucleophilic and electrophilic reagents are described. Particular attention has been devoted to the possibility of using O-alkyl-lactams for the synthesis of various heterocyclic compounds which are of both chemical and biological interest. The bibliography includes 135 references.

UDC: 547.27-318

DOI: 10.1070/RC1969v038n11ABEH001863


 English version:
Russian Chemical Reviews, 1969, 38:11, 913–925


© Steklov Math. Inst. of RAS, 2026