This article is cited in 40 papers

Structure and reactivity of organic compounds (quantitative laws)

V. A. Pal'm

Tartu State University

Abstract: CONTENTS
I. Introduction 471
II. The linear free energy (LFE) relationship 472
III. Effect of structural factors on reactivity. Fundamental principles 472
IV. Inductive constants of substituents 473
V. General applicability of inductive constants of substituents 474
VI. Steric constants of substituents from kinetic data on the acid hydrolysis of esters 475
VII. Quantitative calculation of the hyperconjugation effect 475
VIII. Quantitative calculation of conjugation between π bonds 476
IX. Polar effects of nuclear substituents on the reactivity of aromatic compounds. Hammett's equation 477
X. Polar and steric constants of ortho-substituents 481
XI. Problem of the quantitative separation of inductive and polar conjugative effects 481
XII. Generalisation of the concept of polar constants of substituents 484
XIII. Use of the LFE principle to obtain special correlation equations having a limited range of application 485
XIV. The problem of calculating the field effect 486
XV. Anchimeric assistance 488
XVI. Correlation schemes with a variable reactive centre 488
XVII. Correlation of polarographic half-wave potentials 489
XVIII. Use of the LFE principle for radical reactions 490
XIX. Correlation of dipole moments 490
XX. Some quantitative aspects of the dependence of reactivity on the nature of the solvent 491
XXI. Free energy as the sole universal measure of reactivity 493
XXII. Practical efficiency of linear correlation equations 494
XXIII. Conclusion 495


DOI: 10.1070/RC1961v030n09ABEH002997

 English version: Russian Chemical Reviews, 1961, 30:9, 471–498