È. A. Genina, A. N. Bashkatov, V. V. Tuchin, “Study of diffusion of indocyanine green as a photodynamic dye into skin using backscattering spectroscopy”, Kvantovaya Elektronika, 2014, Volume 44, Number 7,Pages <nobr>689

This article is cited in 10 papers

Laser biophotonics

Study of diffusion of indocyanine green as a photodynamic dye into skin using backscattering spectroscopy

È. A. Genina^a, A. N. Bashkatov^a, V. V. Tuchin^abc

^a OBP Research-Educational Institute of Optics and Biophotonics, Saratov State University
^b Institute of Precision Mechanics and Control, Russian Academy of Sciences, Saratov
^c University of Oulu

Abstract: One of the lines of development of modern medicine is theranostics consisting in simultaneous diagnosis and laser treatment with the use of multifunctional agents such as fluorescent indocyanine green that has photodynamic and photothermal properties. Diffusion of indocyanine green dissolved in water and aqueous solutions of alcohols (glycerol, propylene glycol and ethanol) into the dermis is studied by using backscattering spectroscopy. The coefficients of the dye diffusion into the dermis are obtained for the first time by using these solvents.

Keywords: indocyanine green, dermis, backscattering spectroscopy, diffusion coefficient.

PACS: 87.15.Vv, 87.64.Cc

Received: 10.04.2014
Revised: 17.05.2014