This article is cited in 38 papers

Image processing

Spatial-frequency Fourier polarimetry of the complex degree of mutual anisotropy of linear and circular birefringence in the diagnostics of oncological changes in morphological structure of biological tissues

Yu. A. Ushenko, M. P. Gorskii, A. V. Dubolazov, A. V. Motrich, V. A. Ushenko, M. I. Sidor

Chernivtsi National University

Abstract: Theory of polarisation-correlation analysis of laser images of histological sections of biopsy material from cervix tissue based on spatial frequency selection of linear and circular birefringence mechanisms is formulated. Comparative results of measuring the coordinate distributions of the complex degree of mutual anisotropy (CDMA), produced by fibrillar networks formed by myosin and collagen fibres of cervix tissue in different pathological conditions, namely, pre-cancer (dysplasia) and cancer (adenocarcinoma), are presented. The values and variation ranges of statistical (moments of the first — fourth order), correlation (excess-autocorrelation functions), and fractal (slopes of approximating curves and dispersion of extrema of logarithmic dependences of power spectra) parameters of the CDMA coordinate distributions are studied. Objective criteria for pathology diagnostics and differentiation of its severity degree are determined.

Keywords: laser, polarisation, Fourier filtration, correlation, biological tissue, birefringence, crystal, statistical moment, fractal.

PACS: 07.60.Fs, 42.25.Lc, 87.19.xj

Received: 11.02.2012
Revised: 27.04.2012

 English version: Quantum Electronics, 2012, 42:8, 727–732

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