O. V. Ulianova, S. S. Ul'yanov, P. Li, Q. Luo, “Estimation of reactogenicity of preparations produced on the basis of photoinactivated live vaccines against brucellosis and tularaemia on the organismic level. 2. Using the method of speckle-microscopy with high spatial resolution”, Kvantovaya Elektronika, 2011, Volume 41, Number 4,Pages <nobr>344

This article is cited in 1 paper

Optical technologies in biophysics and medicine

Estimation of reactogenicity of preparations produced on the basis of photoinactivated live vaccines against brucellosis and tularaemia on the organismic level. 2. Using the method of speckle-microscopy with high spatial resolution

O. V. Ulianova^ab, S. S. Ul'yanov^a, P. Li^c, Q. Luo^c

^a Saratov State University named after N. G. Chernyshevsky
^b Saratov State Agrarian University named after N. I. Vavilov
^c Huazhong University of Science and Technology, Wuhan, China

Abstract: The method of speckle microscopy was adapted to estimate the reactogenicity of the prototypes of vaccine preparations against extremely dangerous infections. The theory is proposed to describe the mechanism of formation of the output signal from the super-high spatial resolution speckle microscope. The experimental studies show that bacterial suspensions, irradiated in different regimes of inactivation, do not exert negative influence on the blood microcirculations in laboratory animals.

PACS: 05.45.Df, 42.30.Ms, 87.64.Aa, 87.64.Cc

Received: 25.02.2011