This article is cited in 23 papers

Application of lasers and laser-optical methods in life sciences

Non-invasive, MRI-compatible fibreoptic device for functional near-IR reflectometry of human brain

H. S. S. Sorvoja^a, T. S. Myllylä^a, M. Yu. Kirillin^b, E. A. Sergeeva^b, R. A. Myllylä^a, A. A. Elseoud^c, J. Nikkinen^c, O. Tervonen^c, V. Kiviniemi<sup>c

a</sup> Optoelectronics and Measurements Techniques Laboratory, University of Oulu, Finland
^b Institute of Applied Physics, Russian Academy of Sciences, Nizhny Novgorod
^c MRI Research Unit, Department of Diagnostic Radiology, Oulu University Hospital, Finland

Abstract: A non-invasive device for measuring blood oxygen variations in human brain is designed, implemented, and tested for MRI compatibility. The device is based on principles of near-IR reflectometry; power LEDs serve as sources of probing radiation delivered to patient skin surface through optical fibres. Numerical Monte Carlo simulations of probing radiation propagation in a multilayer brain model are performed to evaluate signal levels at different source — detector separations at three operation wavelengths and an additional wavelength of 915 nm. It is shown that the device can be applied for brain activity studies using power LEDs operating at 830 and 915 nm, while employment of wavelength of 660 nm requires an increased probing power. Employment of the wavelength of 592 nm in the current configuration is unreasonable.

PACS: 87.64.Cc, 07.60.Vg

Received: 28.10.2010

 English version: Quantum Electronics, 2010, 40:12, 1067–1073

Bibliographic databases:

• 
• 
•