This article is cited in 1 paper

Proceedings of The XXV Annual International Conference "Saratov Fall Meeting 2021", September 27-October 1, 2021, Saratov, Russia
Biophotonics

Influence of the duration of circadian rhythm dis-turbance by light exposure on the morphology of the liver of laboratory rats

S. S. Pakhomy, O. V. Zlobina, I. O. Bugaeva, G. N. Maslyakova, A. N. Ivanov, A. O. Moskvina

Saratov State Medical University named after V. I. Razumovsky

Abstract: We studied the effect of long-term constant light exposure on the severity and reversibility of morphological changes in the liver of laboratory rats. Modeling of light exposure was carried out by means of 24-hour exposure to artificial light (in the daytime – 300 lk, at night – 500 lk). During the study we found that morphological changes in the liver were represented by damage to the parenchyma and circulatory disorders, the degree of which increased with increasing duration of exposure. After providing natural light in the laboratory, gradual recovery of the morphological structure of the organ was observed, which indicates the reversibility of the changes detected.

Keywords: light exposure, circadian rhythms, morphology, liver.

Received: 20.12.2021
Revised: 17.01.2022
Accepted: 23.03.2022

DOI: 10.21883/OS.2022.06.52627.34-22

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