This article is cited in 8 papers

Communications

Irregular cationic lipotetrapeptides for pharmaceutical multifunctional transport systems

Z. G. Denieva^ab, U. A. Budanova^a, Yu. L. Sebyakin<sup>a

a</sup> M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation
^b A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: New cationic branched lipotetrapeptides based on l-amino acids and higher alkanols were prepared. Study of their physicochemical and membrane-forming properties revealed that phase transition temperature of these amphiphiles locates in the range of physiological norm. The particle sizes of liposomal dispersions with high aggregation stability are in dimension applicable to penetrate into small blood vessels.

Language: English

DOI: 10.1016/j.mencom.2021.07.024

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