Communications

Synthesis of new [1,2,4]triazolo[5',1':2,3]pyrimido[4,5-b]indol-2-amines

N. I. Vikrishchuk^a, O. P. Demidov<sup>b

a</sup> Department of Chemistry, Southern Federal University, 344090 Rostov-on-Don, Russian Federation
^b Department of Chemistry, North-Caucasus Federal University, 355017 Stavropol, Russian Federation

Abstract: The reaction of 2-chloroindole-3-carbaldehydes with 3,5-diamino-1,2,4-triazole under basic conditions affords new 10H-[1,2,4]triazolo[5',1':2,3]pyrimido[4,5-b]indol-2-amines representing a novel heterocyclic system. The structure of the obtained compounds is confirmed by IR, ¹H and ¹³C NMR spectroscopy and X-ray diffraction analysis.

Keywords: indoles, [1,2,4]triazolo[5',1':2,3]pyrimido[4,5-b]indole, 3,5-diamino-1,2,4-triazole, heterocyclization, X-ray structural analysis.

Received: 06.10.2025
Accepted: 01.12.2025

Language: English

DOI: 10.71267/mencom.7932