Communications

Photochemical synthesis of 3,4-dihydro-1-benzoxepine-2,5-diones from 2-formylaryl acrylates

S. A. Krasnova^a, A. Yu. Smirnov^ab, V. A. Ikonnikova^a, A. A. Mikhaylov^ab, M. S. Baranov^ab, D. S. Ivanov<sup>a

a</sup> M. M. Shemyakin–Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russian Federation
^b N. I. Pirogov Russian National Research Medical University, 117997 Moscow, Russian Federation

Abstract: Photochemical method for synthesizing benzoxepine-2,5 diones via LED (light-emitting diode) irradiation of 2-formylaryl acrylates is presented. The reaction affords products in moderate to good yields (23–91%), its mechanism is discussed.

Keywords: 2-formylaryl acrylates, benzoxepine-2,5-diones, photochemical cyclization, ortho-substituted benzaldehydes, salicylaldehyde.

Received: 31.07.2025
Accepted: 03.10.2025

Language: English

DOI: 10.71267/mencom.7890