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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 1996 Volume 6, Issue 4, Pages 153–154 (Mi mendc4957)

This article is cited in 6 papers

Synthetic nucleases triggered by mild acidification: a new type of biologically active compounds

I. Ya. Levitina, V. M. Belkova, G. N. Novodarovaa, Z. A. Shabarovab, M. E. Vol'pina

a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
b Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: Alkylcobalt chelates possessing tridentate Schiff bases display nuclease activity upon proton-assisted homolytic decomposition, due to the formation of both alkyl free radicals and a cobalt complex catalysing the autooxidation of organic substrates.

Language: English

DOI: 10.1070/MC1996v006n04ABEH000624



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