This article is cited in 3 papers

Methyl 2-trifluoromethylaziridine-2-carboxylate: stereodirected N-halogenation from the sterically more hindered side

V. V. Rozhkov^a, K. N. Makarov^b, S. N. Osipov^b, I. I. Chervin^a, A. V. Ignatenko^c, R. G. Kostyanovsky<sup>a

a</sup> N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Moscow, Russian Federation
^b A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^c N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: N-Fluorination and N-chlorination of methyl 2-trifluoromethylaziridine-2-carboxylate occurs predominantly from the more hindered side owing to the fixed orientation of the lone electron pair of the N atom caused by the formation of an intramolecular H-bond.

Language: English

DOI: 10.1070/MC1997v007n06ABEH000831

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