This article is cited in 4 papers

Communications

Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol

I. V. Galkina^a, V. V. Andriyashin^a, S. R. Romanov^a, S. N. Egorova^b, N. V. Vorob'eva^b, M. P. Shulaeva^c, O. K. Pozdeev^c, I. A. Litvinov^d, Yu. V. Bakhtiyarova<sup>a

a</sup> Alexander Butlerov Institute of Chemistry, Kazan Federal University, Kazan, Russian Federation
^b Kazan State Medical University, Kazan, Russian Federation
^c Kazan State Medical Academy, Kazan, Russian Federation
^d A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of the Russian Academy of Sciences, Kazan, Russian Federation

Abstract: New biologically active quaternary bis-phosphonium salts were obtained by quaternization of 4-bromomethyl-2,6-di-tert-butylphenol with several α,ω,-bis(diphenylphosphino)-alkanes. All synthesized compounds demonstrated high antibacterial and antifungal activities against pathogenic microflora of humans and animals.

Keywords: quaternary phosphonium salts, 2,6-di-tert-butyl-4-methylphenol, sterically hindered phenols, antibacterial activity, antifungal activity.

Language: English

DOI: 10.1016/j.mencom.2023.09.014

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