This article is cited in 8 papers

Direct conversion of N-ethylamines into functionalised amides by S₂Cl₂

L. S. Konstantinova^a, O. A. Rakitin^a, Ch. W. Rees<sup>b

a</sup> N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b Department of Chemistry, Imperial College London, London, UK

Abstract: Hünig's base 1 is known to react extensively with S₂Cl₂ to give monocyclic, bicyclic and fused tricyclic 1,2-dithioles with the N-ethyl group intact, but with S₂Cl₂ and DABCO in chloroform at 0 °C 1 is converted into dichloroacetamide 2 by selective reaction of the N-ethyl group in a new one-pot transformation; ethyl-substituted derivatives of 1, diethylisopropylamine 17 and triethylamine react similarly though the last, less bulky, amine also gives trichloroacetamide 20.

Language: English

DOI: 10.1070/MC2001v011n05ABEH001504

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