This article is cited in 6 papers

Communications

Photocatalytic reduction of fluoroalkyl-substituted alcohols activated by pentafluoropyridine

S. S. Lunkov^ab, A. A. Zemtsov^a, V. V. Levin^a, A. D. Dilman<sup>a

a</sup> N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation

Abstract: A new method for deoxygenation of fluoroalkyl-substituted alcohols involves derivatization of the hydroxy group with pentafluoropyridine followed by photoredox catalyzed reduction of the obtained hetaryl ethers using γ-terpinene as a source of hydrogen. The initial alcohols can be easily obtained by nucleophilic fluoroalkylation of the corresponding aldehydes.

Keywords: photocatalysis, radicals, deoxygenation, organofluorine compounds, alcohols, ethers.

Language: English

DOI: 10.1016/j.mencom.2023.04.028

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