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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2005 Volume 15, Issue 1, Pages 20–21 (Mi mendc3657)

This article is cited in 6 papers

New routes to 1,2-dithiole-3-thiones and 3-imines

V. A. Ogurtsova, O. A. Rakitina, Ch. W. Reesb, A. A. Smolentseva, K. A. Lyssenkoc

a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
b Department of Chemistry, Imperial College London, London, UK
c A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation

Abstract: The reaction of readily available 3,4,5-trichloro-1,2-dithiolium chloride 1 and 4,5-dichloro-1,2-dithiole-3-thione 2 with o-substituted anilines provides a simple route to 1,2-dithiole-3-thiones and 3-imines, which can be cyclised to give new, more complex heterocyclic systems such as 1,2-dithiolo[4,3-b][1,4]benzoxazine of potential value in cancer chemotherapy

Language: English

DOI: 10.1070/MC2005v015n01ABEH002057



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