This article is cited in 2 papers

Communications

One-pot multi-component synthesis and cytotoxic activity of terpenoid dimers containing azapolycyclic spacers

E. B. Rakhimova^a, V. Yu. Kirsanov^a, U. Sh. Kuzmina^b, Yu. V. Vakhitova<sup>b

a</sup> Institute of Petrochemistry and Catalysis, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation
^b Institute of Biochemistry and Genetics, Ufa Federal Research Center of the Russian Academy of Sciences, Ufa, Russian Federation

Abstract: Novel terpenoid dimers linked through the E–E rings were synthesized by catalytic multicomponent condensation of amino derivatives of methyl maleopimarate with form-aldehyde and dimethyl-tetraazadecalin or tetraazaperhydro- tetracene. Primary screening of the synthesized terpenoid dimers for cytotoxic activity was performed.

Keywords: heterocyclization, maleopimaric acid, terpenoids, zeolite, polycycles, cytotoxic activity.

Language: English

DOI: 10.1016/j.mencom.2023.01.020

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