This article is cited in 9 papers

Enzymatic resolution of (±)-venlafaxine

K. A. Kochetkov, M. A. Galkina, O. M. Galkin

A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation

Abstract: Lipase-catalyzed acylation of the racemic venlafaxine with vinyl acetate in chloroform at 20°C gives its (R)-enantiomer and (S)-acetate, the ee value of the latter being>99%.

Language: English

DOI: 10.1016/j.mencom.2010.11.003

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