This article is cited in 9 papers

Communications

Ornithine and lysine based lipotripeptides: synthesis and comparison of transfection efficiency

O. O. Koloskova, U. A. Budanova, A. M. Sumina, G. A. Sarychev, Yu. L. Sebyakin

M.V. Lomonosov Institute of Fine Chemical Technologies, MIREA - Russian Technological University, Moscow, Russian Federation

Abstract: The derivatives of aliphatic tripeptides containing l-ornithine, l-lysine and diesters of l-glutamic acid were synthesized, the physico- chemical properties of dispersions based on them were examined and the dependence of transfection efficiency on the amphiphile:DNA ratio and the structure of the peptides was evaluated.

Language: English

DOI: 10.1016/j.mencom.2014.09.004

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