This article is cited in 8 papers

Communications

Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates

A. G. Gerbst, N. E. Ustyuzhanina, N. E. Nifantiev

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: Computer docking studies suggest an explanation for better anticoagulant activity of fucosylated chondroitin sulfates as compared to non-fucosylated ones due to the formation of the ternary complex with thrombin and antithrombin III.

Language: English

DOI: 10.1016/j.mencom.2015.11.006

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