This article is cited in 9 papers

Communications

Nucleophilic aromatic cine-substitution of hydrogen: the ionic liquid-promoted von Richter reaction

M. A. Epishina^a, A. S. Kulikov^a, N. V. Ignat'ev^b, M. Schulte^b, N. N. Makhova<sup>a

a</sup> N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
^b Ionic Liquid Research Laboratory, Merck KGaA, Darmstadt, Germany

Abstract: Conversion of 4-R-nitrobenzenes into 3-R-benzoic acids under the action of KCN in the EtOH–H₂O mixture (the von Richter reaction) is significantly accelerated by ionic liquids thus allowing to extend the scope of the reaction. The finding is pioneering ionic liquid- promoted nucleophilic aromatic cine-substitution of hydrogen.

Language: English

DOI: 10.1016/j.mencom.2015.01.015

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