This article is cited in 11 papers

Communications

Synthesis of hybrid structures comprising diaziridine and cyclopropane rings in one molecule

V. V. Kuznetsov, V. V. Kachala, N. N. Makhova

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Abstract: A facile, diastereoselective method for the synthesis of diaziridines with C- and N-cyclopropyl substituents has been developed, N-cyclopropyldiaziridines being for the first time synthesized. The method is based on one-pot three-component condensation of cyclopropyl-containing carbonyl compounds, primary aliphatic amines including cyclopropylamine, and N-chloroalkylamines in organic solvents in the presence of bases under mild conditions.

Language: English

DOI: 10.1016/j.mencom.2018.09.015

Bibliographic databases:

•