This article is cited in 5 papers

Communications

Metal-free protocol for the synthesis of novel 6-(het)aryl-5-aryl-5H-imidazo[4,5-b][1,2,5]oxadiazolo[3,4-e]pyrazines

Yu. A. Kvashnin^a, G. L. Rusinov^ab, V. N. Charushin<sup>ab

a</sup> I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
^b Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation

Abstract: New 5-aryl-5H-imidazo[4,5-b][1,2,5]oxadiazolo[3,4-e]pyrazines with the 6-positioned electron-rich (het)aryl substituents have been obtained from 5,6-diamino[1,2,5]oxadiazolo[3,4-b]pyrazines through the effective two-step strategy: the starting diamino compounds were treated with triethyl orthoformate, followed by the reaction with a π-excessive arene in thepresence of trifluoroacetic acid. The structures of target products were for the first time confirmed by X-ray diffraction analysis.

Language: English

DOI: 10.1016/j.mencom.2018.09.002

Bibliographic databases:

•