This article is cited in 16 papers

Communications

‘Click’ synthesis of cobalt bis(dicarbollide)–cholesterol conjugates

A. A. Druzina^a, A. V. Shmalko^a, E. P. Andreichuk^ab, O. B. Zhidkova^a, I. D. Kosenko^a, A. A. Semioshkin^ac, I. B. Sivaev^ad, S. Mandal^e, Zh. Shen^f, V. I. Bregadze<sup>a

a</sup> A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
^b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
^c Globalchempharm Company, Moscow, Russian Federation
^d G.V. Plekhanov Russian University of Economics, Moscow, Russian Federation
^e Indian Institute of Science Education and Research, Kolkata, Mohanpur, India
^f Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, Zhe-jiang, China

Abstract: New conjugates of cholesterol and cobalt bis(dicarbollide) were synthesized using ‘click’ cycloaddition of 3b-(2-azidoethyl) cholest-5-ene and acetylene-equipped cobalt bis(dicarbollides). The synthesized boronated cholesterols can be of interest for liposomal drug delivery for boron neutron capture therapy of cancer.

Language: English

DOI: 10.1016/j.mencom.2019.11.007

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