This article is cited in 2 papers

Communications

Reactions of functionally substituted bicyclo[4.2.2]deca-2,4,7,9-tetraenes with m-chloroperbenzoic acid and in vitro evaluation Of Product Cytotoxicity against tumor cells

V. A. D'yakonov, G. N. Kadikova, G. F. Gazizullina, I. R. Ramazanov, L. U. Dzhemileva, U. M. Dzhemilev

Institute of Petrochemistry and Catalysis, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation

Abstract: The oxidation of functionally substituted bicyclo[4.2.2]deca-2,4,7,9-tetraenes with m-chloroperbenzoic acid affords practically valuable 8-oxatricyclo[4.3.2.0^7,9]undeca-2,4,10-trienes and bicyclo[4.3.1]deca-2,4,8-triene-7,10-diols in yields of 65–72%. The structures of the products were established by advanced spectral methods and X-ray diffraction analysis. The new compounds were screened for in vitro cytotoxicity against Jurkat, K562, U937 and HL60 tumor cell lines.

Language: English

DOI: 10.1016/j.mencom.2019.09.013

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