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JOURNALS // Mendeleev Communications // Archive

Mendeleev Commun., 2019 Volume 29, Issue 3, Pages 320–322 (Mi mendc1510)

This article is cited in 13 papers

Communications

Formulation, drug release features and in vitro cytotoxic evaluation of nonionic mixed surfactant stabilized water-in-oil microemulsion loaded with doxorubicin

N. E. Sedyakinaa, A. F. Krivoshchepovb, A. Ya. Zasypkob, A. G. Demchenkoa, A. L. Rozofarova, V. N. Kuryakovc, N. B. Feldmana, S. V. Lutsenkoa

a I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation
b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
c Oil and Gas Research Institute of the Russian Academy of Sciences, Moscow, Russian Federation

Abstract: New water-in-oil microemulsion, based on paraffin oil, polyglycerol polyricinoleate and Tween 80, has been formulated and used as encapsulation matrix for doxorubicin. Drug release features and in vitro cytotoxicity for the formulation has been evaluated.

Language: English

DOI: 10.1016/j.mencom.2019.05.027



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