This article is cited in 4 papers

Communications

Reaction of nonstabilized azomethine ylides with Mannich bases: an approach to 3-acylpyrrolidines

E. V. Gorbunova, E. M. Buev, V. S. Moshkin, V. Ya. Sosnovskikh

Institute of Natural Sciences and Mathematics, Ural Federal University, Ekaterinburg, Russian Federation

Abstract: Mannich bases obtained from cycloalkanones and methyl-ketones decompose on heating to give α,β-enones, which react in situ with nonstabilized azomethine ylides formed from spiro[anthracene-oxazolidines]. The final products, 3-acylpyrrolidines, were obtained in yields of 21–79% by heating the starting compounds in a microwave reactor in o-xylene at 210°C for 45min

Language: English

DOI: 10.1016/j.mencom.2019.03.008

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