This article is cited in 4 papers

Communications

Mesoporous polymer network produced from N-vinylpyrrolidone and triethylene glycol dimethacrylate as potential macromolecularly imprinted material and oligopeptide carrier

N. V. Fadeeva, E. I. Knerelman, G. I. Davydova, N. S. Emelyanova, S. V. Kurmaz

Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation

Abstract: An original approach is proposed for creating the molecularly imprinted polymer and the carrier of protein molecules. Specifically, a thermally and chemically stable branched N-vinylpyrrolidone copolymer was used as the model of an imprint biomolecule and the porogen in the three-dimensional radical copolymerization of N-vinylpyrrolidone and triethylene glycol dimethacrylate. Removal of the branched copolymer left cavities available for binding biomolecules to the copolymer matrix due to its mesoporous structure.

Keywords: N-vinylpyrrolidone, molecularly imprinted polymers, carrier, oligopeptide, mesoporous polymer network, non-covalent biomolecular imprinting, melanotan II, adsorption.

Language: English

DOI: 10.1016/j.mencom.2020.11.016

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