This article is cited in 4 papers

Brief Communications

Monitoring of propofol and its metabolite during total intravenous anesthesia

A. Yu. Elizarov^a, T. D. Ershov^a, A. I. Levshankov<sup>b

a</sup> Ioffe Institute, St. Petersburg
^b Kirov Medical Force Academy, St. Petersburg

Abstract: Intravenous hypnotic propofol and its metabolite are detected in real time during total intravenous anesthesia by an electron ionization mass spectrometer. The mass spectrometer is connected directly to the breathing circuit of an apparatus for inhalational anesthesia. Ratios between the propofol concentrations in expired air and blood serum are measured. It is concluded that real-time noninvasive monitoring of the propofol concentration in blood using electron ionization mass spectrometry is feasible.

Received: 28.02.2011
Accepted: 27.04.2011

 English version: Technical Physics, 2011, 56:12, 1807–1810

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