Abstract:Background and Objectives: The influence of low-voltage electrical current impulses on arterial blood microcirculation was investigated using the method of laser Doppler flowmetry. Materials and Methods: The method involves measuring the blood microcirculation index by quantifying the Doppler frequency shift arising when the microcirculatory bed is probed with laser radiation, followed by the registration of radiation reflected from both moving and stationary tissue components. Results: It has been demonstrated that exposure to electrical current impulses leads to an average 4-fold increase in the myogenic component of the spectrum relative to the baseline sample. This increase is associated with changes in the tone of the vascular wall in blood arterioles. The predominance of neurogenic components of the spectrum after cessation of exposure to electrical impulses has also been revealed. Conclusion: Utilizing the laser Doppler flowmetry method based on the amplitudes of spectral harmonics of vascular oscillation rhythms allows to determine quantitatively the changes in blood flow regulation during exposure to current impulses.
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