This article is cited in 1 paper

Biophysics and Medical Physics

Study of ethanol impact on the transepidermal transport of indocyanine green with backscattering spectroscopy

E. A. Genina^ab, A. N. Bashkatov^ba, V. V. Tuchin<sup>abc

a</sup> Saratov State University
^b Tomsk State University
^c Institute of Precision Mechanics and Control of Russian Academy of Sciences

Abstract: In the work, impact of aqueous $40\%$-ethanol solution on the transepidermal transport of photodynamic dye indocyanine green has been studied with backscattering spectroscopy. It has been first obtained the value of the dye diffusion coefficient through the stratum corneum ex vivo at the use of ethanol as a diffusion enhancer: $(6.85\pm3.75)\times10^{-7}$ cm$^{2}$/s.

Keywords: indocyanine green, epidermal stratum corneum, diffusion coefficient, backscattering spectroscopy.

UDC: 535.361.22:577.3

DOI: 10.18500/1817-3020-2016-16-2-91-96