This article is cited in 2 papers

Physics

Influence of 40$\%$-glucose solution on a human corneal structure

A. S. Orlova^a, A. N. Bashkatov^b, È. A. Genina^b, I. O. Kolbenev^a, I. D. Kamenskikh^a, T. G. Kamenskikh^a, V. V. Tuchin<sup>bcd

a</sup> Saratov State Medical University
^b Saratov State University
^c University of Oulu
^d Institute of Precision Mechanics and Control, Russian Academy of Sciences, Saratov

Abstract: Effective treatment of the patients with postoperative corneal edema is one of the actual problems in ophthalmology. In this paper results of complex monitoring of influence of 40$\%$-glucose solution on the state of both normal and edematous cornea after a cataract phacoemulsification on the base of date of confocal microscopy and optical coherence tomography have been presented. It has been shown that the glucose solution induces a short-term swelling of the healthy cornea and dehydration of the edematous one, as well as optical clearing of the tissue in the both cases. The influence of the glucose solution on the state of both epithelial and endothelial corneal layers has been studied. The obtained results allow one to extend the possibilities of the monitoring of both structural and optical corneal parameters during the treatment.

Keywords: control of tissue optical properties, optical coherence tomography, confocal microscopy, cornea, cataract, glucose.

UDC: 535.015; 53.06; 617.7; 616-073.756.8(04); 617.713-085; 617.741-089; 57.085.1

DOI: 10.18500/1817-3020-2014-14-1-11-19