Abstract:
A single-sheet graphene (through which an electric current is passed) encapsulated by a massive semiconductor substrate and an organic macromolecule (biomolecule-antibody) is considered as a resistive biosensor. The organic macromolecule (biomolecule-antigen) being tested is placed on top of the antibody. Expressions for the concentrations of current carriers in graphene before and after the antigen placement are obtained within the framework of simple models. The conditions under which the presence of an antigen changes the type of conductivity of graphene are determined.