This article is cited in 4 papers

Semiconductors

Performance analysis of graphene-coated GaAs SPR sensor for detection of DNA hybridization

A. Pathak, M. Meena, S. Tripathi

Department of Electronics and Communication Engineering, Motilal Nehru National Institute of Technology, Allahabad, 211004, India

Abstract: The present paper provides a numerical analysis of DNA hybridization occurrence on graphene-coated GaAs SPR sensor (SF10 prism–Au–GaAs–Graphene–Phosphate buffer saline (PBS) solution). The angular interrogation method is used to comprehend sensor performance through SPR curves. Single-stranded DNA present in PBS solution, on hybridization with its complementary DNA, results in desorption from nanostructures, enabling detection of DNA hybridization event. The proposed SPR sensor shows remarkable performance for detection of DNA hybridization, with sensitivity $\sim$153.32$^\circ$ per refractive index unit (RIU), detection accuracy $\sim$0.62 deg$^{-1}$, and quality factor $\sim$9.45 RIU$^{-1}$.

Keywords: SPR sensor, DNA hybridization, angular interrogation method, Kretschmann configuration, surface plasmon waves.

Received: 20.10.2020
Revised: 20.10.2020
Accepted: 28.10.2020

Language: English

 English version: Physics of the Solid State, 2021, 63:3, 453–459