This article is cited in 6 papers

ANALYSIS AND MODELING OF COMPLEX LIVING SYSTEMS

Wavelet-based analysis of cell dynamics measured by interference microscopy

A. R. Brazhe^a, N. A. Brazhe^a, O. V. Sosnovtseva^b, A. N. Pavlov^c, E. Mosekilde^b, G. V. Maksimov<sup>a

a</sup> Moscow State University, Biological Faculty, MSU, 1, building 12, GSP-1, Leninskiye Gory, Moscow, 119991, Russia
^b Technical University of Denmark, Physics Department, Anker Engelunds Vej 1, building 307, 2800 Kgs. Lyngby, Denmark
^c Chernyshevsky Saratov State University, Physical Faculty, Astrachanskaya str. 83, Saratov, 410012, Russia

Abstract: Laser interference microscopy was used to study morphology and intracellular dynamics of erythrocytes, neurons and mast cells. We have found that changes of the local refractive index (RI) of cells have regular components that relate to the cooperative processes in the cellular submembrane and centre regions. We have shown that characteristic frequencies of RI dynamics differ for various cell types and can be used as markers of specific cellular processes.

Keywords: laser interference microscopy, wavelet-based analysis.

Received: 15.04.2008
Revised: 02.06.2008

DOI: 10.20537/2076-7633-2009-1-1-77-83